Implications of cannabinoids in diseases neurological
Preparations of Cannabis sativa (marijuana) are used for many centuries both for medical purposes and for recreational use. Recent advances in understanding of the pharmacological properties especially of delta9-tetrahydrocannabinol (Delta9-THC) and the physiological roles of endocannabinoids led to the development of new strategies in the treatment of psychiatric disorders and neurological ones. Potential uses of cannabinoid receptor antagonists include the management of spasticity and tremor in multiple sclerosis and spinal injury, pain, inflammatory disorders, glaucoma, bronchial asthma, cancer and vasodilation associated with the advanced form cirrhosis. Of CB1 receptor antagonists have, however, therapeutic potential in Parkinson's disease.
Alsasua Del Valle A, Cell Mol Neurobiol 2006
0 comments:
Post a Comment